{"id":603,"date":"2026-04-18T17:56:27","date_gmt":"2026-04-18T17:56:27","guid":{"rendered":"https:\/\/thuoc115.com\/suckhoe\/?p=603"},"modified":"2026-04-18T18:39:12","modified_gmt":"2026-04-18T18:39:12","slug":"che-pham-duong-man-linh-tri-tieu-duong-khang-tri-glucose","status":"publish","type":"post","link":"https:\/\/thuoc115.com\/suckhoe\/che-pham-duong-man-linh-tri-tieu-duong-khang-tri-glucose\/","title":{"rendered":"ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng kh\u00e1ng tr\u1ecb glucose"},"content":{"rendered":"\n<p>Ph\u01b0\u01a1ng ph\u00e1p x\u00e1c \u0111\u1ecbnh 14 th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc trong ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh.<\/p>\n\n\n\n<p><strong>L\u0129nh v\u1ef1c k\u1ef9 thu\u1eadt<\/strong><br>Ph\u00e1t minh n\u00e0y thu\u1ed9c l\u0129nh v\u1ef1c \u1ee9ng d\u1ee5ng y h\u1ecdc c\u1ed5 truy\u1ec1n hi\u1ec7n \u0111\u1ea1i, \u0111\u1eb7c bi\u1ec7t li\u00ean quan \u0111\u1ebfn ph\u01b0\u01a1ng ph\u00e1p ki\u1ec3m tra c\u00e1c th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc trong ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh.<\/p>\n\n\n\n<p><strong>B\u1ed1i c\u1ea3nh k\u1ef9 thu\u1eadt<\/strong><br>Ho\u00e0n \u0110\u01b0\u1eddng M\u1eabn Linh \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n d\u1ef1a tr\u00ean b\u00e0i thu\u1ed1c \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e2m s\u00e0ng l\u00e0 hi\u1ec7u qu\u1ea3 \u2013 \u201cKhai u\u1ea5t thanh v\u1ecb\u201d d\u1ea1ng c\u1ed1m, sau \u0111\u00f3 \u0111\u01b0\u1ee3c gia gi\u1ea3m v\u00e0 c\u1ea3i ti\u1ebfn d\u1ea1ng b\u00e0o ch\u1ebf.<\/p>\n\n\n\n<p>Ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh g\u1ed3m 10 v\u1ecb thu\u1ed1c th\u01b0\u1eddng d\u00f9ng: <strong>Ho\u00e0ng li\u00ean, \u0110\u1ea1i ho\u00e0ng, Ho\u00e0ng c\u1ea7m, B\u1ea1ch th\u01b0\u1ee3c, S\u00e0i h\u1ed3, Ch\u1ec9 th\u1ef1c, S\u01a1n tra, \u00d4 mai, B\u00e1n h\u1ea1, Thi\u00ean hoa ph\u1ea5n.<\/strong><\/p>\n\n\n\n<p>B\u00e0i thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng: khai u\u1ea5t thanh v\u1ecb, t\u01b0 \u00e2m gi\u00e1ng h\u1ecfa, th\u00f4ng ph\u1ee7 t\u1ea3 tr\u1ecdc.<\/p>\n\n\n\n<p>Quan s\u00e1t l\u00e2m s\u00e0ng cho th\u1ea5y thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng c\u1ea3i thi\u1ec7n r\u00f5 r\u1ec7t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type II, \u0111\u1eb7c bi\u1ec7t hi\u1ec7u qu\u1ea3 v\u1edbi b\u1ec7nh nh\u00e2n giai \u0111o\u1ea1n s\u1edbm \u2013 trung b\u00ecnh v\u00e0 c\u00f3 th\u1ec3 tr\u1ea1ng b\u00e9o. \u0110\u1ed3ng th\u1eddi, c\u00e1c th\u00ed nghi\u1ec7m d\u01b0\u1ee3c l\u00fd cho th\u1ea5y \u0110\u01b0\u1eddng M\u1eabn Linh c\u00f3 th\u1ec3 t\u0103ng \u0111\u00e1ng k\u1ec3 \u0111\u1ed9 nh\u1ea1y insulin \u1edf m\u00f4 h\u00ecnh chu\u1ed9t \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng g\u00e2y b\u1edfi kh\u1ea9u ph\u1ea7n gi\u00e0u n\u0103ng l\u01b0\u1ee3ng v\u00e0 chu\u1ed9t m\u1eafc \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type II t\u1ef1 ph\u00e1t.<\/p>\n\n\n\n<p>\u0110\u1ec3 chu\u1ea9n h\u00f3a s\u1ea3n xu\u1ea5t thu\u1ed1c v\u00e0 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 r\u00f5 r\u00e0ng, ch\u1ea5t l\u01b0\u1ee3ng \u1ed5n \u0111\u1ecbnh, c\u1ea7n ph\u1ea3i x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c c\u00e1c th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc trong ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh.<\/p>\n\n\n\n<p>Trong c\u00e1c th\u00e0nh ph\u1ea7n d\u01b0\u1ee3c ch\u1ea5t c\u00f3 th\u1ec3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c bao g\u1ed3m:<br>Naringin, Baicalin, Neohesperidin, Berberin hydroclorid, Baicalein, Wogonin, Hesperidin, Jatrorrhizin hydroclorid, Coptisin hydroclorid, Wogonoside, Palmatin hydroclorid, Naringenin, Oroxylin A, Chrysin.<\/p>\n\n\n\n<p>C\u00e1c ch\u1ea5t n\u00e0y \u0111\u1ec1u l\u00e0 c\u00e1c h\u1ee3p ch\u1ea5t \u0111\u00e3 bi\u1ebft. \u0110\u1ec3 ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng ch\u1ebf ph\u1ea9m m\u1ed9t c\u00e1ch to\u00e0n di\u1ec7n h\u01a1n, c\u1ea7n x\u00e2y d\u1ef1ng ti\u00eau chu\u1ea9n ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng ph\u00f9 h\u1ee3p v\u1edbi hi\u1ec7n \u0111\u1ea1i h\u00f3a y h\u1ecdc c\u1ed5 truy\u1ec1n, do \u0111\u00f3 c\u1ea7n m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ph\u00e2n t\u00edch c\u00f3 th\u1ec3 \u0111\u1ed3ng th\u1eddi x\u00e1c \u0111\u1ecbnh nhi\u1ec1u th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc trong ch\u1ebf ph\u1ea9m.<\/p>\n\n\n\n<p><strong>N\u1ed9i dung ph\u00e1t minh<\/strong><br>Nh\u1eb1m chu\u1ea9n h\u00f3a s\u1ea3n xu\u1ea5t thu\u1ed1c \u0110\u01b0\u1eddng M\u1eabn Linh, \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 r\u00f5 r\u00e0ng v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng \u1ed5n \u0111\u1ecbnh, ph\u00e1t minh n\u00e0y cung c\u1ea5p m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p x\u00e1c \u0111\u1ecbnh 14 ho\u1ea1t ch\u1ea5t trong ch\u1ebf ph\u1ea9m. Ph\u01b0\u01a1ng ph\u00e1p s\u1eed d\u1ee5ng s\u1eafc k\u00fd l\u1ecfng hi\u1ec7u n\u0103ng cao (HPLC) \u0111\u1ec3 \u0111\u1ecbnh l\u01b0\u1ee3ng \u0111\u1ed3ng th\u1eddi c\u00e1c ho\u1ea1t ch\u1ea5t n\u00e0y.<\/p>\n\n\n\n<p>Ph\u01b0\u01a1ng ph\u00e1p c\u00f3 \u0111\u1ed9 ch\u00ednh x\u00e1c, \u0111\u1ed9 nh\u1ea1y v\u00e0 \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh cao, \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m \u0111\u1ea1t ti\u00eau ch\u00ed: \u201can to\u00e0n, \u0111\u1ed3ng nh\u1ea5t, \u1ed5n \u0111\u1ecbnh, hi\u1ec7u qu\u1ea3 v\u00e0 c\u00f3 th\u1ec3 ki\u1ec3m so\u00e1t\u201d.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>https:\/\/patents.google.com\/patent\/CN103575821A\/zh<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>T\u1ef7 l\u1ec7 b\u00e0i thu\u1ed1c (d\u1ea1ng \u201cph\u1ea7n\u201d)<\/strong><\/h2>\n\n\n\n<p>C\u00f3, nh\u01b0ng <strong>kh\u00f4ng ph\u1ea3i gam c\u1ee5 th\u1ec3<\/strong>, m\u00e0 l\u00e0 kho\u1ea3ng:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Thi\u00ean hoa ph\u1ea5n: 10\u201330 ph\u1ea7n<\/li>\n\n\n\n<li>S\u00e0i h\u1ed3: 10\u201330 ph\u1ea7n<\/li>\n\n\n\n<li>Ch\u1ec9 th\u1ef1c: 3\u201315 ph\u1ea7n<\/li>\n\n\n\n<li>\u0110\u1ea1i ho\u00e0ng: 1\u20136 ph\u1ea7n<\/li>\n\n\n\n<li>B\u00e1n h\u1ea1: 1\u201312 ph\u1ea7n<\/li>\n\n\n\n<li>Ho\u00e0ng c\u1ea7m: 3\u201315 ph\u1ea7n<\/li>\n\n\n\n<li>Ho\u00e0ng li\u00ean: 1\u201312 ph\u1ea7n<\/li>\n\n\n\n<li>B\u1ea1ch th\u01b0\u1ee3c: 3\u201315 ph\u1ea7n<\/li>\n\n\n\n<li>\u00d4 mai: 5\u201320 ph\u1ea7n<\/li>\n\n\n\n<li>S\u01a1n tra: 3\u201315 ph\u1ea7n<\/li>\n<\/ul>\n\n\n\n<p>&#x1f449; \u201cPh\u1ea7n\u201d = t\u1ef7 l\u1ec7 t\u01b0\u01a1ng \u0111\u1ed1i, kh\u00f4ng ph\u1ea3i gam c\u1ed1 \u0111\u1ecbnh<br>\u2192 Ng\u01b0\u1eddi s\u1ea3n xu\u1ea5t c\u00f3 th\u1ec3 scale:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1 ph\u1ea7n = 1g<\/li>\n\n\n\n<li>ho\u1eb7c 1 ph\u1ea7n = 10g<\/li>\n\n\n\n<li>ho\u1eb7c 1 ph\u1ea7n = 100g<\/li>\n<\/ul>\n\n\n\n<p>Ho\u00e0ng k\u1ef3 (Astragalus) \u2013 b\u1ed5 kh\u00ed, t\u0103ng nh\u1ea1y insulin<br>Sinh \u0111\u1ecba ho\u00e0ng \u2013 d\u01b0\u1ee1ng \u00e2m, thanh nhi\u1ec7t<br>M\u1ea1ch m\u00f4n \u0111\u00f4ng \u2013 d\u01b0\u1ee1ng \u00e2m, sinh t\u00e2n d\u1ecbch<br>Ng\u0169 v\u1ecb t\u1eed \u2013 li\u1ec5m \u00e2m, h\u1ed7 tr\u1ee3 chuy\u1ec3n h\u00f3a<br>Ho\u00e0i s\u01a1n (S\u01a1n d\u01b0\u1ee3c) \u2013 ki\u1ec7n t\u1ef3, \u1ed5n \u0111\u1ecbnh \u0111\u01b0\u1eddng huy\u1ebft<br>Thi\u00ean hoa ph\u1ea5n \u2013 sinh t\u00e2n, thanh nhi\u1ec7t, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft<br>\u0110an s\u00e2m \u2013 ho\u1ea1t huy\u1ebft, c\u1ea3i thi\u1ec7n vi tu\u1ea7n ho\u00e0n<br>K\u1ef7 t\u1eed \u2013 b\u1ed5 can th\u1eadn<br>C\u00e1t c\u0103n \u2013 t\u0103ng chuy\u1ec3n h\u00f3a glucose<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Thi\u00ean hoa ph\u1ea5n: 10\u201330<br>S\u00e0i h\u1ed3: 10\u201330<br>Ch\u1ec9 th\u1ef1c: 3\u201315<br>\u0110\u1ea1i ho\u00e0ng: 1\u20136<br>B\u00e1n h\u1ea1: 1\u201312<br>Ho\u00e0ng c\u1ea7m: 3\u201315<br>Ho\u00e0ng li\u00ean: 1\u201312<br>B\u1ea1ch th\u01b0\u1ee3c: 3\u201315<br>\u00d4 mai: 5\u201320<br>S\u01a1n tra: 3\u201315<\/p>\n\n\n\n<p><strong>Shenqi Jiangtang granule<\/strong><\/p>\n\n\n\n<p>So s\u00e1nh v\u1edbi metformin tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng<\/p>\n\n\n\n<p>https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7542533<\/p>\n\n\n\n<p>C\u00e1c th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a ch\u1ebf ph\u1ea9m Shenqi Jiangtang granules bao g\u1ed3m: nh\u00e2n s\u00e2m, ginsenosid, ho\u00e0ng k\u1ef3, m\u1ea1ch m\u00f4n, ph\u00fac b\u1ed3n t\u1eed (m\u00e2m x\u00f4i), thi\u00ean hoa ph\u1ea5n (trichosanthin), \u0111\u1ecba ho\u00e0ng, ph\u1ee5c linh, k\u1ef7 t\u1eed, tr\u1ea1ch t\u1ea3, ng\u0169 v\u1ecb t\u1eed v\u00e0 s\u01a1n d\u01b0\u1ee3c.<\/p>\n\n\n\n<p>C\u00e1c nghi\u00ean c\u1ee9u d\u01b0\u1ee3c l\u00fd hi\u1ec7n \u0111\u1ea1i cho th\u1ea5y ginsenosid c\u00f3 th\u1ec3 s\u1eeda ch\u1eefa t\u1ebf b\u00e0o \u03b2 c\u1ee7a \u0111\u1ea3o t\u1ee5y, th\u00fac \u0111\u1ea9y ti\u1ebft insulin, \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 \u1ee9c ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a alloxan v\u00e0 c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Hi\u1ec7u qu\u1ea3 v\u00e0 t\u00ednh an to\u00e0n c\u1ee7a y h\u1ecdc c\u1ed5 truy\u1ec1n Trung Qu\u1ed1c trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng: M\u1ed9t th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean, c\u00f3 \u0111\u1ed1i ch\u1ee9ng, m\u00f9 \u0111\u00f4i<\/p>\n\n\n\n<p>B\u1ed1i c\u1ea3nh (Background)<\/p>\n\n\n\n<p>Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng b\u1eb1ng Y h\u1ecdc c\u1ed5 truy\u1ec1n Trung Qu\u1ed1c c\u00f3 l\u1ecbch s\u1eed l\u00e2u \u0111\u1eddi. M\u1ee5c ti\u00eau c\u1ee7a nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 x\u00e1c \u0111\u1ecbnh t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a vi\u1ec7c k\u1ebft h\u1ee3p thu\u1ed1c y h\u1ecdc c\u1ed5 truy\u1ec1n v\u1edbi glibenclamide trong \u0111i\u1ec1u tr\u1ecb \u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2.<\/p>\n\n\n\n<p>Ph\u01b0\u01a1ng ph\u00e1p (Methods)<\/p>\n\n\n\n<p>Trong m\u1ed9t th\u1eed nghi\u1ec7m \u0111\u1ed1i ch\u1ee9ng, m\u00f9 \u0111\u00f4i, \u0111a trung t\u00e2m theo thi\u1ebft k\u1ebf kh\u00f4ng thua k\u00e9m (non-inferiority), 800 b\u1ec7nh nh\u00e2n c\u00f3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft ch\u01b0a \u0111\u1ea1t y\u00eau c\u1ea7u (\u0111\u01b0\u1eddng huy\u1ebft \u0111\u00f3i 7\u201313 mmol\/L v\u00e0 HbA1c 7\u201311%) \u0111\u01b0\u1ee3c ph\u00e2n ng\u1eabu nhi\u00ean v\u00e0o hai nh\u00f3m:<\/p>\n\n\n\n<p>Nh\u00f3m d\u00f9ng Xiaoke Pill (m\u1ed9t ch\u1ebf ph\u1ea9m th\u1ea3o d\u01b0\u1ee3c k\u1ebft h\u1ee3p v\u1edbi glibenclamide)<br>Nh\u00f3m d\u00f9ng Glibenclamide<\/p>\n\n\n\n<p>Hai nh\u00f3m n\u00e0y l\u1ea1i \u0111\u01b0\u1ee3c chia th\u00e0nh:<\/p>\n\n\n\n<p>Nh\u00f3m ch\u01b0a t\u1eebng d\u00f9ng thu\u1ed1c (drug-na\u00efve)<br>Nh\u00f3m \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00f3 b\u1eb1ng \u0111\u01a1n tr\u1ecb li\u1ec7u Metformin<\/p>\n\n\n\n<p>C\u00e1c ch\u1ec9 s\u1ed1 \u0111\u00e1nh gi\u00e1 sau 48 tu\u1ea7n bao g\u1ed3m:<\/p>\n\n\n\n<p>T\u1ef7 l\u1ec7 v\u00e0 t\u1ea7n su\u1ea5t h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft<br>M\u1ee9c thay \u0111\u1ed5i trung b\u00ecnh HbA1c<br>T\u1ef7 l\u1ec7 b\u1ec7nh nh\u00e2n \u0111\u1ea1t HbA1c &lt; 6,5%<br>K\u1ebft qu\u1ea3 (Findings)<\/p>\n\n\n\n<p>Nh\u00f3m ch\u01b0a d\u00f9ng thu\u1ed1c tr\u01b0\u1edbc \u0111\u00f3:<\/p>\n\n\n\n<p>T\u1ed5ng t\u1ef7 l\u1ec7 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft gi\u1ea3m 38% (p = 0,024)<br>H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft nh\u1eb9 gi\u1ea3m 41% (p = 0,002)<br>&#x1f449; so v\u1edbi nh\u00f3m d\u00f9ng glibenclamide<\/p>\n\n\n\n<p>Nh\u00f3m \u0111\u00e3 d\u00f9ng metformin:<\/p>\n\n\n\n<p>T\u1ea7n su\u1ea5t h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft trung b\u00ecnh h\u00e0ng n\u0103m gi\u1ea3m 62% (p = 0,003)<\/p>\n\n\n\n<p>Hi\u1ec7u qu\u1ea3 HbA1c:<\/p>\n\n\n\n<p>Nh\u00f3m ch\u01b0a d\u00f9ng thu\u1ed1c:<br>Xiaoke Pill: \u22120,70%<br>Glibenclamide: \u22120,66%<br>Ch\u00eanh l\u1ec7ch: \u22120,04% (\u22120,20 \u0111\u1ebfn 0,12)<br>Nh\u00f3m metformin:<br>Xiaoke Pill: \u22120,45%<br>Glibenclamide: \u22120,59%<br>Ch\u00eanh l\u1ec7ch: 0,14% (\u22120,12 \u0111\u1ebfn 0,39)<\/p>\n\n\n\n<p>T\u1ef7 l\u1ec7 \u0111\u1ea1t HbA1c &lt; 6,5%:<\/p>\n\n\n\n<p>Nh\u00f3m ch\u01b0a d\u00f9ng thu\u1ed1c: 26,6% vs 23,4%<br>Nh\u00f3m metformin: 20,1% vs 18,9%<br>Di\u1ec5n gi\u1ea3i (Interpretation)<\/p>\n\n\n\n<p>\u1ede b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft ch\u01b0a t\u1ed1t, \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Xiaoke Pill gi\u00fap:<\/p>\n\n\n\n<p>Gi\u1ea3m \u0111\u00e1ng k\u1ec3 nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft<br>Hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft t\u01b0\u01a1ng \u0111\u01b0\u01a1ng glibenclamide sau 48 tu\u1ea7n<\/p>\n\n\n\n<p>T\u1ea1i Trung Qu\u1ed1c, m\u1ed9t s\u1ed1 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng l\u00e0 c\u00e1c ch\u1ebf ph\u1ea9m ph\u1ed1i h\u1ee3p gi\u1eefa d\u01b0\u1ee3c li\u1ec7u y h\u1ecdc c\u1ed5 truy\u1ec1n v\u00e0 thu\u1ed1c t\u00e2y, ch\u1eb3ng h\u1ea1n nh\u01b0 Glibenclamide.<\/p>\n\n\n\n<p>M\u1ed9t trong nh\u1eefng ch\u1ebf ph\u1ea9m \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i l\u00e0 Xiaoke Pill [11], trong \u0111\u00f3 m\u1ed7i vi\u00ean ch\u1ee9a 0,25 microgam glibenclamide [12].<\/p>\n\n\n\n<p>C\u00e1c th\u00e0nh ph\u1ea7n th\u1ea3o d\u01b0\u1ee3c bao g\u1ed3m:<\/p>\n\n\n\n<p>C\u00e1t c\u0103n (Radix Puerariae)<br>\u0110\u1ecba ho\u00e0ng (Radix Rehmanniae)<br>Ho\u00e0ng k\u1ef3 (Radix Astragali)<br>Thi\u00ean hoa ph\u1ea5n (Radix Trichosanthis)<br>R\u00e2u ng\u00f4 (Stylus Zeae Maydis)<br>Ng\u0169 v\u1ecb t\u1eed (Fructus Schisandrae Sphenantherae)<br>S\u01a1n d\u01b0\u1ee3c (Rhizoma Dioscoreae)<\/p>\n\n\n\n<p>C\u00e1c v\u1ecb n\u00e0y \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn t\u1eeb hai ph\u01b0\u01a1ng thu\u1ed1c c\u1ed5 \u0111i\u1ec3n \u0111i\u1ec1u tr\u1ecb ch\u1ee9ng \u201cti\u00eau kh\u00e1t\u201d l\u00e0:<\/p>\n\n\n\n<p>Yuquan San [13]<br>Xiaoke Fang [14]<\/p>\n\n\n\n<p>Vi\u1ec7c l\u1ef1a ch\u1ecdn c\u00e1c th\u00e0nh ph\u1ea7n th\u1ea3o d\u01b0\u1ee3c n\u00e0y \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng d\u1ef1a tr\u00ean l\u00fd lu\u1eadn c\u1ee7a y h\u1ecdc c\u1ed5 truy\u1ec1n.<\/p>\n\n\n\n<p>C\u00e1c nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y c\u00f4ng b\u1ed1 tr\u00ean c\u00e1c t\u1ea1p ch\u00ed y h\u1ecdc t\u1ea1i Trung Qu\u1ed1c cho th\u1ea5y Xiaoke Pill c\u1ea3i thi\u1ec7n r\u00f5 r\u1ec7t c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng. Tuy nhi\u00ean, hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n c\u1ee7a Xiaoke Pill tr\u01b0\u1edbc \u0111\u00e2y ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 b\u1eb1ng c\u00e1c th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean, m\u00f9 \u0111\u00f4i, c\u00f3 \u0111\u1ed1i ch\u1ee9ng gi\u1ea3 d\u01b0\u1ee3c.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>The main components of Shenqi Jiangtang granules are ginseng, ginsenosides,\u00a0<em>Astragalus<\/em>,\u00a0<em>Ophiopogon japonicus<\/em>, raspberry, trichosanthin,\u00a0<em>Rehmannia glutinosa<\/em>, poria, medlar,\u00a0<em>Alisma<\/em>,\u00a0<em>Schisandra<\/em>, and yam.<\/p>\n\n\n\n<p>https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3584095<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Nghi\u00ean c\u1ee9u v\u1ec1 ho\u00e0ng k\u1ef3 v\u00e0 sinh \u0111\u1ecba<\/p>\n\n\n\n<p>https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8662558<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u0111an s\u00e2m ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 2<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7886461<\/p>\n\n\n\n<p>ch\u1eefa c\u00e1c bi\u1ebfn ch\u1ee9ng tim m\u1ea1ch c\u1ee7a ti\u1ec3u \u0111\u01b0\u1eddng<\/p>\n\n\n\n<p>https:\/\/www.mdpi.com\/1422-0067\/25\/16\/8986<\/p>\n<!-- relpost-thumb-wrapper --><div class=\"relpost-thumb-wrapper\"><!-- filter-class --><div class=\"relpost-thumb-container\"><style>.relpost-block-single-image, .relpost-post-image { margin-bottom: 10px; }<\/style><h3>Related posts:<\/h3><div style=\"clear: both\"><\/div><div style=\"clear: both\"><\/div><!-- relpost-block-container --><div class=\"relpost-block-container relpost-block-column-layout\" style=\"--relposth-columns: 3;--relposth-columns_t: 2; --relposth-columns_m: 2\"><a href=\"https:\/\/thuoc115.com\/suckhoe\/lam-sang-to-co-che-dieu-tri-cua-cay-rau-meo-orthosiphon-aristatus-trong-benh-than-do-tang-acid-uric\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-hidden=\"true\" role=\"img\" data-bg=\"https:\/\/thuoc115.com\/suckhoe\/wp-content\/plugins\/related-posts-thumbnails\/img\/default.png\" style=\"background: transparent no-repeat scroll 0% 0%; width: 150px; height: 150px; aspect-ratio: 1\/1;\"><\/div><div class=\"relpost-block-single-text\"  style=\"height: 75px;font-family: Arial;  font-size: 12px;  color: #333333;\"><h2 class=\"relpost_card_title\">L\u00e0m s\u00e1ng t\u1ecf c\u01a1 ch\u1ebf \u0111i\u1ec1u tr\u1ecb c\u1ee7a c\u00e2y r\u00e2u m\u00e8o (Orthosiphon aristatus) trong b\u1ec7nh th\u1eadn do t\u0103ng acid uri...<\/h2><\/div><\/div><\/a><a href=\"https:\/\/thuoc115.com\/suckhoe\/len-men-trai-nhau-cho-benh-ly-tieu-duong-viem-khop\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-hidden=\"true\" role=\"img\" data-bg=\"https:\/\/thuoc115.com\/suckhoe\/wp-content\/plugins\/related-posts-thumbnails\/img\/default.png\" style=\"background: transparent no-repeat scroll 0% 0%; width: 150px; height: 150px; aspect-ratio: 1\/1;\"><\/div><div class=\"relpost-block-single-text\"  style=\"height: 75px;font-family: Arial;  font-size: 12px;  color: #333333;\"><h2 class=\"relpost_card_title\">L\u00ean men tr\u00e1i nh\u00e0u cho b\u1ec7nh l\u00fd ti\u1ec3u \u0111\u01b0\u1eddng, vi\u00eam kh\u1edbp<\/h2><\/div><\/div><\/a><a href=\"https:\/\/thuoc115.com\/suckhoe\/dieu-tri-roi-loan-nhip-tim-dua-tren-co-che-bang-cac-hop-chat-thuc-vat-va-thao-duoc\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-hidden=\"true\" role=\"img\" data-bg=\"https:\/\/thuoc115.com\/suckhoe\/wp-content\/plugins\/related-posts-thumbnails\/img\/default.png\" style=\"background: transparent no-repeat scroll 0% 0%; width: 150px; height: 150px; aspect-ratio: 1\/1;\"><\/div><div class=\"relpost-block-single-text\"  style=\"height: 75px;font-family: Arial;  font-size: 12px;  color: #333333;\"><h2 class=\"relpost_card_title\">\u0110i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n nh\u1ecbp tim d\u1ef1a tr\u00ean c\u01a1 ch\u1ebf b\u1eb1ng c\u00e1c h\u1ee3p ch\u1ea5t th\u1ef1c v\u1eadt v\u00e0 th\u1ea3o d\u01b0\u1ee3c<\/h2><\/div><\/div><\/a><\/div><!-- close relpost-block-container --><div style=\"clear: both\"><\/div><\/div><!-- close filter class --><\/div><!-- close relpost-thumb-wrapper -->","protected":false},"excerpt":{"rendered":"<p>Ph\u01b0\u01a1ng ph\u00e1p x\u00e1c \u0111\u1ecbnh 14 th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc trong ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh. L\u0129nh v\u1ef1c k\u1ef9 thu\u1eadtPh\u00e1t minh n\u00e0y thu\u1ed9c l\u0129nh v\u1ef1c \u1ee9ng d\u1ee5ng y h\u1ecdc c\u1ed5 truy\u1ec1n hi\u1ec7n \u0111\u1ea1i, \u0111\u1eb7c bi\u1ec7t li\u00ean quan \u0111\u1ebfn ph\u01b0\u01a1ng ph\u00e1p ki\u1ec3m tra c\u00e1c th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc trong ch\u1ebf ph\u1ea9m \u0110\u01b0\u1eddng M\u1eabn Linh. 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